Among other factors, your healthcare provider should tell you to stop taking BELVIQ/BELVIQ XR if you haven't achieved
at least 5% weight loss by the end of the first 12 weeks of treatment.
During the clinical studies, 44% of patients taking BELVIQ (n=3098) and 51% of patients using diet and exercise alone
(n=3038) withdrew prior to Week 52. The average baseline body weight was 221.3 lb for BELVIQ and 220.9 lb for
Though BELVIQ is not a treatment for high cholesterol or high blood pressure, adults taking BELVIQ with diet and
exercise had significant improvements in their blood pressure and cholesterol levels, compared with those using diet
and exercise alone.
It is not known if BELVIQ changes your risk of heart problems, stroke, or death due to heart problems or stroke.
BELVIQ may help keep weight off
In one study, adults taking BELVIQ 10 mg twice daily were able to lose weight and maintain weight loss for up to 2 years. Patients in all groups who completed the study including those on diet and exercise alone, regained some weight, but they remained under their starting weight.
BELVIQ may help overweight/obese patients living with type 2 diabetes lose weight
BELVIQ 10 mg twice daily was also studied in overweight men and women with type 2 diabetes. During the study, 251
adults received BELVIQ, while 248 adults used diet and exercise alone. The results showed that over a third of
adults (37.5%) taking BELVIQ lost 5% or more of their body weight, compared with those using diet and exercise alone
(16.1%). And 16.3% of adults taking BELVIQ with diet and exercise lost 10% or more of their body weight, compared
with those using diet and exercise alone (4.4%). Though BELVIQ is not a treatment for type 2 diabetes, the group
showed significant improvement in blood sugar levels, compared with adults using diet and exercise alone.
During the study, 34% of patients taking BELVIQ and 38% of patients using diet and exercise alone withdrew prior to
Patients with type 2 diabetes treated with BELVIQ were 4 times* more likely to achieve at least 10% weight
loss compared with diet and exercise alone.
*This data was determined based upon odds ratio. Odds ratio is the likelihood
of achieving the weight loss goal with medication versus with diet and exercise alone.
The most common side effects for BELVIQ were headache, dizziness, fatigue, nausea, dry mouth, constipation, low blood
sugar (in patients with type 2 diabetes), and back pain.
Discontinuation rates due to side effects were similar between BELVIQ and placebo (8.6% and 6.7%, respectively). The
most common side effects leading to discontinuation more often with BELVIQ than placebo were headache, depression,