Proven Results with BELVIQ® 10 mg Twice Daily

Clinically Proven to Work 

BELVIQ, 10 mg twice daily, can help you lose weight and improve certain health risk factors. In FDA clinical trials, people who added BELVIQ to diet and exercise were able to lose weight and improve health risk factors, such as high blood pressure, high blood sugar, and high cholesterol levels. BELVIQ was tested in two major clinical studies, one lasting a year (4,008 people) and one lasting 2 years (3,182 people).* Though it is not a blood pressure treatment, BELVIQ may lower blood pressure.

The combined results of these two studies showed that:

  • Almost half of people (47.1%) taking BELVIQ lost 5% or more of their body weight after 1 year of treatment, compared with those using diet and exercise alone (22.6%)

  • Some (22.4%) lost as much as 10% or more of their body weight after 1 year of treatment, compared with those using diet and exercise alone (8.7%)

People taking BELVIQ with diet and exercise had significant improvements in their blood pressure and cholesterol levels, compared with those using diet and exercise alone. It is not known if BELVIQ changes your risk of heart problems, stroke, or death due to heart problems or stroke.

BELVIQ® can help you manage your weight loss — In a major clinical trial, people taking BELVIQ
10 mg twice daily were able to lose weight and maintain weight loss up to 2 years. In the 2-year study, almost half of people who completed the first year continued on in year 2. Patients in all groups who completed the study regained weight but remained below their starting weight.

BELVIQ® helps overweight people with type 2 diabetes lose weight — BELVIQ 10 mg twice daily was also tested in a study involving 604* overweight men and women with type 2 diabetes. Results showed that more than a third of people taking BELVIQ with diet and exercise (37.5%) lost 5% or more of their body weight, compared with those using diet and exercise alone (16.1%). In the same study, the BELVIQ group showed significant improvements in blood sugar levels, compared with those using diet and exercise alone.

The most common side affects for BELVIQ were headache, dizziness, fatigue, nausea, dry mouth, constipation, low blood sugar (in patients with type 2 diabetes), and back pain.

*Nearly half of all participants completed the studies in overweight patients without diabetes; nearly two-thirds of the participants completed the study in overweight patients with diabetes.


Also available BELVIQ XR® 

Once-Daily BELVIQ XR® provides support throughout the day. Each 20 mg orange-colored tablet releases medicine in your body throughout the day. The approval of Once-Daily BELVIQ XR® 20 mg extended-release tablet is based on the results of a clinical study which found this formulation to be bioequivalent (i.e., performs in the same manner) to the twice-daily BELVIQ® 10 mg immediate-release tablet.

The bioequivalence and bioavailability of Once-Daily BELVIQ XR 20 mg compared with twice-daily BELVIQ 10 mg was based on a Phase 1 registrational clinical trials among healthy adult subjects. Bioequivalence was demonstrated between BELVIQ XR and BELVIQ.

Important Safety Information

Valvular heart disease: Some people taking medicines like BELVIQ or BELVIQ XR have had heart valve problems. Call your Healthcare Provider right away if you experience trouble breathing; swelling of the arms, legs, ankles, or feet; dizziness, fatigue, or weakness that will not go away; or fast or irregular heartbeat. Before taking BELVIQ or BELVIQ XR, tell your Healthcare Provider if you have or have had heart problems.

Please see additional Important Safety Information below for BELVIQ® and BELVIQ XR®.

Our Discussion Guide Can Help You Talk to Your Healthcare Provider About Weight-Loss Treatment Options.
Save on BELVIQ®and BELVIQ XR®
Get ongoing savings.*
*Restrictions Apply
BELIEVE EVERYDAY
SUPPORT®
It’s your time. Take advantage of our exclusive support program, featuring expert advice, recipes, and tools from our partner at EatingWell®. And be sure to check out the physical activity and food intake app to help you track your progress!
Watch our TV Commercial for BELVIQ®

What is BELVIQ® and BELVIQ XR®?

BELVIQ® and BELVIQ XR® are FDA-approved prescription weight-loss medications that, when used with diet and exercise, can help some overweight (Body Mass Index (BMI) 27 kg/m2) adults with a weight-related medical problem, or obese (BMI 30 kg/m2) adults, lose weight and keep it off.

It is not known if  BELVIQ or BELVIQ XR when taken with other prescription, over-the-counter, or herbal weight-loss products is safe and effective. It is not known if BELVIQ or BELVIQ XR changes your risk of heart problems, stroke, or death due to heart problems or stroke.

Important Safety Information

  • Pregnancy: Do not take if you are pregnant or planning to become pregnant, as weight loss offers no potential benefit during pregnancy and BELVIQ or BELVIQ XR may harm your unborn baby.
  • Hypersensitivity Reactions: Do not take if you are allergic to either of these medicines or any of their ingredients.
  • Serotonin Syndrome or Neuroleptic Malignant Syndrome (NMS)-like reactions: Before using, tell your Healthcare Provider about all the medicines you take, especially medicines that treat depression, migraines, mental problems, or the common cold. These medicines may cause serious or life-threatening side effects if taken with BELVIQ or BELVIQ XR. Call your Healthcare Provider right away if you experience agitation, hallucinations, confusion, or other changes in mental status; coordination problems; uncontrolled muscle spasms; muscle twitching; restlessness; racing or fast heartbeat; high or low blood pressure; sweating; fever; nausea; vomiting; diarrhea; or stiff muscles.
  • Valvular heart disease: Some people taking medicines like BELVIQ or BELVIQ XR have had heart valve problems. Call your Healthcare Provider right away if you experience trouble breathing; swelling of the arms, legs, ankles, or feet; dizziness, fatigue, or weakness that will not go away; or fast or irregular heartbeat. Before taking BELVIQ or BELVIQ XR, tell your Healthcare Provider if you have or have had heart problems.
  • Changes in attention or memory: BELVIQ or BELVIQ XR may slow your thinking. You should not drive a car or operate heavy equipment until you know how BELVIQ or BELVIQ XR affects you.
  • Mental problems: Taking too much BELVIQ or BELVIQ XR may cause hallucinations, a feeling of being high or in a very good mood, or feelings of standing outside your body.
  • Depression or thoughts of suicide: Call your Healthcare Provider right away if you notice any mental changes, especially sudden changes in your mood, behaviors, thoughts, or feelings, or if you have depression or thoughts of suicide.
  • Low blood sugar: Weight loss can cause low blood sugar in people taking medicines for type 2 diabetes, such as insulin or sulfonylureas. Blood sugar levels should be checked before and while taking BELVIQ or BELVIQ XR. Changes to diabetes medication may be needed if low blood sugar develops.
  • Painful erections: If you have an erection lasting more than 4 hours while on BELVIQ or BELVIQ XR, stop taking BELVIQ or BELVIQ XR and call your Healthcare Provider or go to the nearest emergency room right away.
  • Slow heartbeat: Both BELVIQ or BELVIQ XR may cause your heart to beat slower.
  • Decreases in blood cell count: BELVIQ or BELVIQ XR may cause your red and white blood cell counts to decrease.
  • Increase in prolactin: BELVIQ or BELVIQ XR may increase the amount of a hormone called prolactin. Tell your Healthcare Provider if your breasts begin to make milk or a milky fluid, or if you are a male and your breasts increase in size.
  • Most common side effects of BELVIQ® or BELVIQ XR®: Headache, dizziness, fatigue, nausea, dry mouth, constipation, cough, low blood sugar (hypoglycemia) in patients with diabetes, and back pain.
  • Nursing: BELVIQ or BELVIQ XR should not be taken while breastfeeding.
  • Drug interactions: Before taking BELVIQ or BELVIQ XR, tell your Healthcare Provider if you take medicines for depression, migraines, or other medical conditions, such as: triptans; medicines used to treat mood, anxiety, psychotic or thought disorders, including tricyclics, lithium, selective serotonin reuptake inhibitors, selective serotonin-norepinephrine reuptake inhibitors, monoamine oxidase inhibitors, or antipsychotics; cabergoline; linezolid (an antibiotic); tramadol; dextromethorphan (an over-the-counter (OTC) common cold/cough medicine); OTC supplements such as tryptophan or St. John’s Wort; or erectile dysfunction medicines.

BELVIQ and BELVIQ XR are federally controlled substances (CIV) because they may be abused or lead to drug dependence.
For more information about BELVIQ® and BELVIQ XR® talk to your Healthcare Provider and see the full Product Information for BELVIQ®, BELVIQ XR®.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or
call 1-800-FDA-1088.